Current Understanding of Papillary Thyroid Carcinoma
نویسندگان
چکیده
The term thyroid neoplasm incorporates tumors that originate from follicular cells and those arise parafollicular (C cells). Differentiated cancer, which originates cells, includes papillary carcinoma (PTC), (FTC), oncocytic cell (Hürthle), poorly differentiated carcinoma, anaplastic (ATC). PTC tends to have an indolent clinical course with low morbidity mortality. However, this entity has a broad range of biological behavior can result in disease recurrence death, depending on patient tumor characteristics the initial treatment approach. is most common form well-differentiated cancer (WDTC) based recent statistics, accounts for approximately 89.4% all malignancies. appears as irregular solid or cystic nodule normal parenchyma. propensity lymphatic invasion, but it less likely hematogenous spread. Around 11% patients present distant metastases outside neck mediastinum. This manuscript review current understanding epidemiology, pathology, molecular characteristics, prognostic factors, dynamic risk stratification centered evidence-based personalized
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ژورنال
عنوان ژورنال: International Journal of Otolaryngology and Head & Neck Surgery
سال: 2021
ISSN: ['2168-5452', '2168-5460']
DOI: https://doi.org/10.4236/ijohns.2021.103019